To ensure users making use of screen readers can ‘tab’ to your elements, use the Tab Index value in the identity inspector.
For screen readers -> Tab Index value in the identity inspector
This will use the InnerText/HTML of the Button
So if you button is ‘Submit’
It will say ‘Submit, Button’ …blah,blah,blah
For image-based content, make sure you add a description in the ‘Alternate Text’ field for that element in the Identity Inspector.
For image-based content -> ‘Alternate Text’