Embed an HTML „virtual“ directory inside of a Hype

That's not something Hype can do -- this is a format that is meant for the Mac Dashboard (deprecated) and iBooks Author (deprecated).

Have you tried Pubcoder? They might let you embed individual folders with multiple nested assets: Embedding a HTML5 Animation made with Tumult Hype in PubCoder

You wouldn't be using Hype for this, but instead dragging your pano2vr export into Pubcoder.