Audio Video Formats best for Web?

Greetings.
MP4 seems to be the format winner for mobile and desktop, along with maybe WebM.

For video heavy online presentations, can we get away without having to include multiple resource formats for both audio and video? Mp4 and MP3 should catch about 90%+ devices? (according to ChatGPT :D)

Just curious how the Pro's here feel.
Thanks for your comments.

Hi Derek. I got away with mp4 and m4a. I actually did not run into any problems over 6 years of producing media-heavy content.
I think what I'm trying to say is that it's not always possible to be everything for everyone.

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