My experience (and success) with this configuration is minimal, though it is nice to hear that someone else is giving it a try. Officially, Brightsign devices support HTML5, with quite a few caveats and more than a couple “recommendations,” and that fits with my practical attempts at using code generated by HYPE. The result produces very sluggish playback and each time I’ve tested a site, I stop trying and switch to using BrightAuthor, which is bundled for free with Brightsign devices. I wish I had more positive news to report; BrightAuthor works well, but simply can’t do many of the things a web designer has come to expect. My blind guess is that the cause of the sluggishness is a limited ability to handle Javascript, though nothing qualifies me to say so.
On the plus side, depending on your situation, it may be worth giving it another try — Brightsign releases new firmware regularly, and the devices are becoming more and more powerful.
Luke